Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production

Thioredoxin reductases are frequently overexpressed in various solid tumors as a protective mechanism against heightened oxidative stress.Inhibitors of this system, such as Auranofin, are effective in eradicating raceline renegade 8 16x10 cancer cells.However, the clinical significance of thioredoxin reductase 1 (TrxR1) in lung cancer, as well as t

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A longitudinal study of attitudes toward evolution among undergraduates who are members of the Church of Jesus Christ of Latter-day Saints.

Polling data reveal a decades-long residual rejection of evolution in the United States, based on perceived religious conflict.Similarly, a strong creationist movement has been documented internationally, including in the Muslim world.Members of the Church of Jesus Christ of 1.1x1.5 Latter-day Saints (LDS, Mormon), a generally conservative denomina

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